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LungChip

Biorg’s Lung Chip is a layered lung epithelial model grown at the air-liquid interface. Biorg has developed the Lung chip to provide an in vitro testing platform for researchers worldwide. To order, or for more information, please contact us.

Technical Approach

Biorg’s Lung Chip features fully differentiated lung epithelium as shown by the presence of ciliated cells (AcTub), mucin-secreting goblet cells (PAS, MUC5AC, SCGB1A1), and basal epithelial cells (CK5). The lung chip has been successfully applied in toxicology applications.

Lung Chip_Fluor_AcTub_cropped_labeled.webp
Lung Chip_Fluor_CK5_cropped_labeled.webp
Lung Chip_Fluor_MUC5AC_cropped_labeled.webp
Lung Chip_Fluor_SCGB1A1_cropped_labeled.webp
Lung Chip_H&E_cropped.webp
Lung Chip_PAS_cropped_labeled.webp

Intended Applications

Lung Chip is intended for acute and sub-chronic toxicity and mechanistic studies. It offers more comprehensive endpoints than standard 2D primary lung epithelial culture.

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